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Epidermoid carcinoma–derived antimicrobial peptide (ECAP) inhibits phosphorylation by protein kinases in vitro

✍ Scribed by Andriy Hobta; Igor Lisovskiy; Svitlana Mikhalap; Denis Kolybo; Svitlana Romanyuk; Maria Soldatkina; Nataliya Markeyeva; Liudmila Garmanchouk; Svitlana P. Sidorenko; Petro V. Pogrebnoy

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
170 KB
Volume
19
Category
Article
ISSN
0263-6484

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## Abstract S100B(ββ) is a dimeric Ca^2+^‐binding protein that is known to inhibit the protein kinase C (PKC)‐dependent phosphorylation of several proteins. To further characterize this inhibition, we synthesized peptides based on the PKC phosphorylation domains of p53 (residues 367‐388), neuromodu