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Epidermal sphingolipids: Metabolism, function, and roles in skin disorders

✍ Scribed by Walter M. Holleran; Yutaka Takagi; Yoshikazu Uchida

Book ID
116466914
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
352 KB
Volume
580
Category
Article
ISSN
0014-5793

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## Abstract Recent discoveries of two sphingolipid transfer proteins, CERT and FAPP2, have brought the field of sphingolipid metabolism to a more dynamic stage. CERT transfers ceramide from the endoplasmic reticulum (ER) to the Golgi apparatus, a step crucial for sphingomyelin (SM) synthesis. The p