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Epidermal-mesodermal interaction during morphogenesis of the limb regeneration blastema in larval salamanders

✍ Scribed by Stocum, David L. ;Dearlove, George E.

Publisher: John Wiley and Sons
Year: 1972
Tongue: English
Weight: 950 KB
Volume: 181
Category: Article
ISSN: 0022-104X
DOI: 10.1002/jez.1401810106

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✦ Synopsis

The question was asked whether the proximo-distal regional organization of regenerating urodele limbs is the result of a n epidermal-mesodermal interaction, as is the case i n the embryonic limb bud, Epidermal deletion experiments on regeneration blastemas of various stages have answered this question i n the affirmative. The mechanisms involved in the morphogenesis of the regeneration blastema are therefore very similar to those operating in the morphogenesis of embryonic limb buds.

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✍ Kelly, Daryl J. ;Tassava, Roy A. 📂 Article 📅 1973 🏛 John Wiley and Sons 🌐 English ⚖ 795 KB

## Abstract Mitotic activity and RNA synthesis were examined in normal regenerating limbs and denervated non‐regenerating limbs of larval axolotls during the first six days after amputation. H^3^‐uridine incorporation into RNA was measured by autoradiography of deoxyribonuclease treated sections. G