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Epidermal keratinocyte expression of inducible nitric oxide synthase in skin lesions of psoriasis vulgaris

✍ Scribed by Victoria Kolb-Bachofen; Karin Fehsel; Günther Michel; Thomas Ruzicka

Book ID
118555260
Publisher
The Lancet
Year
1994
Tongue
English
Weight
153 KB
Volume
344
Category
Article
ISSN
0140-6736

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## Abstract Nitric oxide (NO) is a small molecule produced during the conversion of l-arginine to l-citrulline by NO synthase (NOS). Several isoforms of NOS exist, of which the Ca2+-independent, inducible NOS (iNOS or NOS2) is most prominently expressed by macrophages. iNOS activity and increased l