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Epidermal growth factor receptor mediates stress-induced expression of its ligands in rat gastric epithelial cells

✍ Scribed by Yoshiji Miyazaki; Shintaro Hiraoka; Syusaku Tsutsui; Shinji Kitamura; Yasuhisa Shinomura; Yuji Matsuzawa

Book ID: 119756095
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 629 KB
Volume: 120
Category: Article
ISSN: 0016-5085
DOI: 10.1053/gast.2001.20950

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## Abstract We have previously shown that the G~q~ protein coupled receptor (G~q~PCR) agonist, carbachol (CCh), transactivates and recruits epidermal growth factor receptor (EGFr)‐dependent signaling mechanisms in intestinal epithelial cells. Increasing evidence suggests that G~q~PCR agonists can a