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Epidermal growth factor receptor in breast carcinoma: association between gene copy number and mutations

✍ Scribed by Ning Lv; Xiaoming Xie; Qidong Ge; Suxia Lin; Xi Wang; Yanan Kong; Hongliu Shi; Xinhua Xie; Weidong Wei

Book ID
115022893
Publisher
BioMed Central
Year
2011
Tongue
English
Weight
498 KB
Volume
6
Category
Article
ISSN
1746-1596

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## Abstract Recent studies have indicated that somatic mutations in the epidermal growth factor receptor (EGFR) gene have been identified in a subset of patients with nonsmall‐cell lung cancer (NSCLC) and are associated with sensitivity to the EGFR‐tyrosine‐kinase inhibitors. These mutations have b