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Epidermal growth factor receptor expression analysis in chemotherapy-naive patients with advanced non-small-cell lung cancer treated with gefitinib or placebo in combination with platinum-based chemotherapy

✍ Scribed by Giuseppe Giaccone; Renee B. Iacona; Abderrahim Fandi; Mette Janas; Judith S. Ochs; Roy S. Herbst; David H. Johnson


Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
494 KB
Volume
135
Category
Article
ISSN
1432-1335

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## Abstract The high frequency of epidermal growth factor receptor (__EGFR__) mutations in tyrosine kinase inhibitor‐responsive non‐small‐cell lung cancer (NSCLC) cases is now well established, highlighting the predictive value of activating __EGFR__ mutations in guiding the clinical use of __EGFR_