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Epidermal growth factor receptor (EGFR) intron 1 polymorphism and clinical outcome in pancreatic adenocarcinoma

✍ Scribed by Andrey Frolov; J. Spencer Liles; Andrew V. Kossenkov; Ching-Wei D. Tzeng; Nirag Jhala; Peter Kulesza; Shyam Varadarajulu; Mohamad Eloubeidi; Martin J. Heslin; J. Pablo Arnoletti

Book ID
116216885
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
954 KB
Volume
200
Category
Article
ISSN
0002-9610

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## Abstract ## BACKGROUND. Erlotinib, in combination with gemcitabine, has shown clinical benefits in pancreatic adenocarcinoma patients. The presence of __EGFR__ mutations and increased __EGFR__ copy numbers in pancreatic adenocarcinoma was explored. ## METHODS. Sixty‐six pancreatic cancer pati