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Epidermal Growth Factor Receptor (EGFR) expression: Prognostic value in breast cancer patients with long-term follow-up

โœ Scribed by R.S. Rampaul; S.E. Pinder; P.M. Wencyk; J.A. Bell; J.F.R. Robertson; R.I. Nicholson; R.W. Blamey; C.W. Elston; I.O. Ellis


Book ID
117657611
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
126 KB
Volume
37
Category
Article
ISSN
0959-8049

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## Abstract The epidermal growth factor receptor (EGFR) has previously been detected in the nucleus of cancer cells and primary tumors. We have reported that EGFR translocates from the plasma membrane to the nucleus. Accumulation of nuclear EGFR is linked to increased DNA synthesis and proliferatio