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Epidermal growth factor, neurotrophins and the metastatic cascade in prostate cancer

✍ Scribed by Ximena Montano; Mustafa B.A Djamgoz

Book ID
116464682
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
266 KB
Volume
571
Category
Article
ISSN
0014-5793

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Epidermal growth factor (EGF) and transforming growth factor-alpha (TGFo0 are two closely related peptides that interact with cell-surface epidermal growth factor receptors (EGFR) to induce receptor tyrosine phosphorylation and activation of intracellular signal-transduction pathways. EGF appears to