Epidermal growth factor in human tear fluid: A minireview
β Scribed by G.-B. Setten; T. Tervo; L. Viinikka; J. Perheentupa; A. Tarkkanen
- Publisher
- Springer Netherlands
- Year
- 1991
- Tongue
- English
- Weight
- 314 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0165-5701
No coin nor oath required. For personal study only.
β¦ Synopsis
This minireview deals with the presence of epidermal growth factor (EGF) in human tear fluid. It explains the occurrence of EGF in tear fluid, the origin of EGF and its dependency on tear fluid dynamics. The alterations in tear fluid EGF concentrations that occur during diseases of the ocular surface are described and discussed in the context of the current knowledge about the interaction between EGF and EGF receptors. The possible clinical implications of topical treatment with EGF are considered.
π SIMILAR VOLUMES
The development of a radioimmunoassay (RIA) for the human epidermal growth factor receptor solubilized with nonionic detergents which employs iodinated epidermal growth factor (125I-EGF) as the specific ligand is described. A monoclonal antibody (R1) that binds specifically to human EGF receptors [W