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Epidermal growth factor (EGF) decreased endothelin-2 (ET-2) production in human renal adenocarcinoma cells

✍ Scribed by Fumino Tokito; Nobuhiro Suzuki; Masaki Hosoya; Hirokazu Matsumoto; Shoichi Ohkubo; Masahiko Fujino


Book ID
115925629
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
396 KB
Volume
295
Category
Article
ISSN
0014-5793

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## Abstract Growth factor receptors of the tyrosine kinase family regulate proliferation of a variety of cell types. In some human cancers, the epidermal growth factor receptor (EGFR) and its ligands often are overexpressed, leading to both constitutive and autocrine activation. Intracellular signa