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Epidermal Growth Factor and Monocyte Chemotactic Peptide-1 Expression in Reflux Nephropathy

✍ Scribed by Boris Chertin; Amicur Farkas; Prem Puri

Book ID: 114218639
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 494 KB
Volume: 44
Category: Article
ISSN: 0302-2838
DOI: 10.1016/s0302-2838(03)00190-8

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## Abstract ## BACKGROUND. Cleavage of membrane‐anchored heparin‐binding epidermal growth factor‐like growth factor (proHB‐EGF) yields a soluble HB‐EGF isoform (sHB‐EGF), which is an activating epidermal growth factor receptor (EGFR) ligand and a C‐terminal fragment HB‐EGF‐C acting directly in the