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Epidermal growth factor and insulin inhibit cell death in pancreatic beta cells by activation of PI3-kinase/AKT signaling pathway under oxidative stress

✍ Scribed by H Maeda; K Gopalrao Rajesh; H Maeda; R Suzuki; S Sasaguri


Book ID
116929888
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
88 KB
Volume
36
Category
Article
ISSN
0041-1345

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## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re