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Epidermal Development and Wound Healing in Matrix Metalloproteinase 13-Deficient Mice

✍ Scribed by Hartenstein, Bettina; Dittrich, Bernd Thilo; Stickens, Dominique; Heyer, Babette; Vu, Thiennu H; Teurich, Sibylle; Schorpp-Kistner, Marina; Werb, Zena; Angel, Peter


Book ID
110049163
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
540 KB
Volume
126
Category
Article
ISSN
0022-202X

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## Abstract Matrix metalloproteinases (MMPs) have been linked to the metastatic potential of tumor cells due to their ability to degrade the extracellular matrix. MMP‐3 (stromelysin‐1) is upregulated in a wide variety of human tumors. We used the MMTV‐PyMT breast cancer model to determine if MMP‐3