Epidemiology of vulvar and vaginal cancer in Germany
β Scribed by C. Dittmer; A. Katalinic; C. Mundhenke; M. Thill; D. Fischer
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 411 KB
- Volume
- 284
- Category
- Article
- ISSN
- 0003-9128
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## Abstract Squamous cell carcinoma (SCC) of the vulva is a heterogeneous disease, associated or not with vulvar lichen sclerosus (LS). The precursor role of LS in vulvar cancer is unclear. We studied the epigenetic alterations of __RASSF1A__, __RASSF2A__, __p16__, __TSPβ1__ and __MGMT__ genes in v
Vulvar cancer is an uncommon disease, marked by typical long delays in diagnosis due to lack of awareness by doctors and patients. The most common histology is squamous, although melanoma, sarcoma and adenocarcinoma occur less frequently. The predictable spread pattern of vulvar cancer to regional t