Epidemiology of esophageal adenocarcinoma
β Scribed by Manuel Pera; Carlos Manterola; Oscar Vidal; Luis Grande
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 114 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0022-4790
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## Abstract Reflux of acidic gastric contents and bile acids into the lower esophagus has been identified to have a central role in esophageal malignancy and is reported to upregulate caudalβrelated homologue 2 (CDX2), a regulatory gene involved in embryonic development and axial patterning of the
In the United States, the incidence of esophageal adenocarcinoma has risen faster than any other malignancy in recent years, and now represents the most common histologic type of esophageal cancer observed in major institutions. The precise etiology of this malignancy, and the epidermiologic variabl
## BACKGROUND. Because very poor survival rates were reported after exclusive nonradical surgery, the current opinion in the medical community is that very few esophageal adenocarcinoma patients can anticipate long-term survival after esophagectomy. In the current study the ability of exclusive ra