## BACKGROUND. The FHIT gene, located at human chromosome 3p14.2, frequently is deleted in a number of human tumors, including breast carcinoma. Its protein product (Fhit) is presumed to have tumor suppressor function. Loss of expression of a tumor suppressor gene is an important step in tumor prog
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Epidemiology of breast carcinoma II: Factors related to the predominance of left-sided disease
โ Scribed by Ruby T. Senie; Paul Peter Rosen; Martin L. Lesser; Ruth E. Snyder; David Schottenfeld; Kathleen Duthie
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 768 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0008-543X
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Use of combined estrogen-progestin hormone replacement therapy appears to be associated with an increased risk of invasive lobular breast carcinomas (ILC) and, to a lesser degree, with risk of invasive ductal carcinoma (IDC). Conceivably, ILCs are more hormonally responsive and so may be more strong