Single-stranded RNA viruses from four different families cause a syndrome of fever and malaise, 'capillary leak' with loss of plasma volume, and coagulation defects which can lead to bleeding. Although direct cytopathic effects can contribute to disease severity, most features of illness are caused
โฆ LIBER โฆ
Epidemiology and pathogenesis of Bolivian hemorrhagic fever
โ Scribed by Patterson, Michael; Grant, Ashley; Paessler, Slobodan
- Book ID
- 121685695
- Publisher
- Elsevier
- Year
- 2014
- Tongue
- English
- Weight
- 616 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1879-6257
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Zoonoses within wild reservoir host populations often occur focally obeying Pavlovskii's rules of "natural nidality". What appears to be a clear example is Bolivian hemorrhagic fever (BHF), a disease endemic to northeastern Bolivia. The etiological agent is Machupo virus (MACV, Arenaviridae). The ve