Epidemiological studies of radio frequency (RF) exposures and human cancers include studies of military and civilian occupational groups, people who live near television and radio transmitters, and users of mobile phones. Many types of cancer have been assessed, with particular attention given to leukemia and brain tumors. The epidemiological results fall short of the strength and consistency of evidence that is required to come to a conclusion that RF emissions are a cause of human cancer. Although the epidemiological evidence in total suggests no increased risk of cancer, the results cannot be unequivocally interpreted in terms of cause and effect. The results are inconsistent, and most studies are limited by lack of detail on actual exposures, short follow-up periods, and the limited ability to deal with other relevant factors. In some studies, there may be substantial biases in the data used. For these same reasons, the studies are unable to confidently exclude any possibility of an increased risk of cancer. Further research to clarify the situation is justified. Priorities include further studies of leukemia in both adults and children, and of cranial tumors in relationship to mobile phone use.