Epidemiological characteristics and response to peginterferon plus ribavirin treatment of hepatitis C virus genotype 4 infection
✍ Scribed by D. Roulot; V. Bourcier; V. Grando; P. Deny; Y. Baazia; H. Fontaine; F. Bailly; L. Castera; V. De Ledinghen; P. Marcellin; R. Poupon; M. Bourlière; J. P. Zarski; F. Roudot-Thoraval; The Observational VHC4 Study Group
- Book ID
- 108885976
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 473 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1352-0504
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## Abstract Variation at the IL‐28B locus was recently reported to be a significant predictive factor of viral response to pegylated‐interferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including IL‐28B polymorphism rs8099917 and v
## Abstract For chronic hepatitis C virus (HCV) infection, evaluation of response to peginterferon (PEG‐IFN) plus ribavirin (RBV) therapy based on viral kinetics is useful as an early predictor of treatment efficacy, but the underlying mechanisms of the different viral kinetics to treatment are sti
In hepatitis C virus (HCV) genotype 1 infection, the duration of interferon-based therapy is a critical determinant in achieving sustained virologic response (SVR). Slow or late responders to peginterferon and ribavirin may benefit from an extended treatment course. We sought to determine if therapy