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Ephrin-A5 modulates cell adhesion and morphology in an integrin-dependent manner

✍ Scribed by Davy, A.

Book ID
111746648
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
916 KB
Volume
19
Category
Article
ISSN
0261-4189

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## Abstract In metastatic cancer, high expression levels of vitronectin (VN) receptors (integrins), FAK, and ERK5 are reported. We hypothesized that integrin‐mediated ERK5 activation via FAK may play a pivotal role in cell adhesion, motility, and metastasis. ERK5 and FAK phosphorylation when metast