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EPHB2germline variants in patients with colorectal cancer or hyperplastic polyposis

✍ Scribed by Antti Kokko; Päivi Laiho; Rainer Lehtonen; Sanna Korja; Luis G Carvajal-Carmona; Heikki Järvinen; Jukka-Pekka Mecklin; Charis Eng; Johanna Schleutker; Ian PM Tomlinson; Pia Vahteristo; Lauri A Aaltonen

Book ID
115010791
Publisher
BioMed Central
Year
2006
Tongue
English
Weight
253 KB
Volume
6
Category
Article
ISSN
1471-2407

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## Abstract It is estimated that up to 35% of colorectal cancers (CRC) can be explained by hereditary factors. However, genes predisposing to highly penetrant CRC syndromes account for only a small fraction of all cases. Thus, most CRCs still remain molecularly unexplained. A recent systematic sequ