Two main characteristics of astrocytes are their elaborated intracellular calcium signaling and their high degree of intercellular communication mediated by gap junctional channels. In these cells a number of studies have contributed to demonstrate that the combination of these two properties provid
EphB signaling inhibits gap junctional intercellular communication and synchronized contraction in cultured cardiomyocytes
โ Scribed by Maki Ishii; Itsuki Mueller; Takayuki Nakajima; Elena B. Pasquale; Kazushige Ogawa
- Book ID
- 106067340
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 663 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0300-8428
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Astrocytes are characterized by extensive intercellular communication mediated primarily by gap junction channels composed of connexin43. To examine this junctional protein in astrocytic functions, astrocytes were cultured from embryonic mice with a null mutation in the connexin43 gene (Reaume et al
Cells rely heavily on cues from their extracellular environment and other cells to coordinate normal physiological processes, and the exchange of molecules via gap junctions has been suggested as an important avenue for cell-cell communication. Gap junctions are found in virtually all mammalian tiss
The effects of extremely low frequency (ELF) magnetic ยฎeld on gap junctional intercellular communication (GJIC), protein levels, and phosphorylation of connexin43 (Cx43) were studied in NIH3T3 cells. The suppression of GJIC by 24 h, 50 Hz, 0.8 mT ELF magnetic ยฎeld, 2 h, 3 ng/ml 12-O-tetradecanoylpho