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Eph receptors and ephrin ligands: embryogenesis to tumorigenesis

โœ Scribed by Dodelet, Vincent C; Pasquale, Elena B

Book ID
110064170
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
133 KB
Volume
19
Category
Article
ISSN
0950-9232

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## Background The tissue distributions and functions of Eph receptors and their ephrin ligands have been well studied, however less is known about their evolutionary history. We have undertaken a phylogenetic analysis of Eph receptors and ephrins from a number of invertebrate and vertebrate species

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โœ Nirmitha I. Herath; Andrew W. Boyd ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 148 KB

## Abstract Eph receptors and their ephrin ligands constitute the largest subfamily of receptor tyrosine kinases and are components of the cell signaling pathways involved during development. Eph and ephrin overexpression have been documented in a variety of human cancers including gastrointestinal