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Eph receptor tyrosine kinases in cancer stem cells

✍ Scribed by Chen, Jin; Song, Wenqiang; Amato, Katherine


Book ID
124119966
Publisher
Elsevier Science
Year
2015
Tongue
English
Weight
694 KB
Volume
26
Category
Article
ISSN
1359-6101

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The Eph family of receptor tyrosine kinases and their cell-presented ligands, the ephrins, are frequently overexpressed in a wide variety of cancers, including breast, small-cell lung and gastrointestinal cancers, melanomas, and neuroblastomas. In particular, one Eph family member, EphA2, is overexp