EPA use of in vivo germ cell mutagenicity data
β Scribed by Michael C. Cimino
- Book ID
- 102189953
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 275 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0893-6692
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
That certain environmental chemicals can induce transmissible mutations in germ cells of experimental mammal is clear. The assumption that under certain conditions these chemicals are also likely to be mutagenic to human germ cells is not detectable. However, it is a difficult challenge to determine
Three metabolites of the industrial chemical 1,3-butadiene (BD), namely butadiene monoepoxide (BMO, 3,4-epoxy-1-butene), diepoxide (DEB, 1,2;3,4-diepoxybutane), and diolepoxide (DE, 3,4- epoxybutane-1,2-diol) were studied for germ cell mutagenicity using the rat spermatid micronucleus (MN) test. All