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Eosinophils as mediators of antibody-dependent damage to schistosomula

✍ Scribed by BUTTERWORTH, A. E.; STURROCK, R. F.; HOUBA, V.; MAHMOUD, A. A. F.; SHER, A.; REES, P. H.

Book ID
109696381
Publisher
Nature Publishing Group
Year
1975
Tongue
English
Weight
299 KB
Volume
256
Category
Article
ISSN
0028-0836

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Killing of Schistosoma mansoni larvae by human eosinophils via antibody-dependent cell-mediated cytotoxicity (ADCC) mechanisms requires adherence between effector cells and parasite targets. The role of adhesion molecules in this mechanism was investigated using blocking monoclonal antibodies (mAb)