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Eosinophilic fasciitis treated with psoralen-ultraviolet A bath photochemotherapy

✍ Scribed by R. Schiener; S.C. Behrens-Williams; P. GottlÖber; H. Pillekamp; R.U. Peter; M. Kerscher

Book ID
104459432
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
424 KB
Volume
142
Category
Article
ISSN
0007-0963

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✦ Synopsis

Eosinophilic fasciitis is a rare disorder which can markedly affect the quality of life in individual patients. So far, no generally accepted and effective treatment modality has been available. Although the precise nature of eosinophilic fasciitis is still unknown, it is often regarded as a variant of localized scleroderma (morphoea). Phototherapy and photochemotherapy have been shown to be effective in the treatment of sclerodermatous skin lesions. We report a patient with eosinophilic fasciitis which was successfully treated with psoralen plus ultraviolet A bath photochemotherapy within 6 months.

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Flegel's disease is an uncommon condition which causes asymptomatic keratotic papules on the limbs. It usually develops in the fourth or fifth decade. Therapeutic options are limited to emollients, topical 5-fluorouracil and retinoids, but none of these treatments is consistently helpful. We report