✦ LIBER ✦
Eosinophil-induced chronic active hepatitis in the idiopathic hypereosinophilic syndrome
✍ Scribed by Anthony Foong; John V. Scholes; Gerald J. Gleich; G. M. Kephart; Peter R. Holt
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 686 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
✦ Synopsis
A 19-yr-old man had features of chronic hepatitis with piecemeal necrosis as the sole clinical feature of the idiopathic hypereosinophilic syndrome. Liver biopsy specimens demonstrated the presence of activated eosinophils and, by immunohistochemical staining, major basic protein in areas of hepatic cell damage. The case demonstrates the clinical presentation of the idiopathic hypereosinophilic syndrome as chronic hepatitis and the association between eosinophil infiltration and degranulation with the presence of hepatocyte necrosis.