Aldol reactions /
Enzymic Synthesis of L-Fucose and Analogs
β Scribed by Wong, Chi-Huey; Alajarin, Ramon; Moris-Varas, Francisco; Blanco, Olga; Garcia-Junceda, Eduardo
- Book ID
- 111881924
- Publisher
- American Chemical Society
- Year
- 1995
- Tongue
- English
- Weight
- 581 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
L-Fucose (4), a sugar widespread in Nature ', has lately acquired special significance as a constituent of several families of blood-group antigens'. L-Fucose is either the immunodominant sugar of complex carbohydrate antigens, or its presence may increase the strength of the antigenic response. Its
## Abstract Fucose is an important component of complex heterooligosaccharides. Here we describe the preparative enzymatic synthesis of ΓβLβfucoseβ1βphosphate as well as its enzymatic conversion into GDPβfucose. Fucose (1) was converted into ΓβLβfucoseβ1βphosphate (2) with fucose kinase (EC 2.7.1.5