Enzymic preparation and characterization of an α-l-β-methylaspartic acid
✍ Scribed by H.A. Barker; R.D. Smyth; E.J. Wawszkiewicz; Mary N. Lee; R.Marilyn Wilson
- Book ID
- 118842175
- Publisher
- Elsevier Science
- Year
- 1958
- Tongue
- English
- Weight
- 528 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0003-9861
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## Abstract The preparation and characterization of α‐L‐glutamic acid oligomers with degree of polymerization (DP) up to 12 are described. The preparation of polymers with low DP corresponding to various __A__/__I__ ratios (where __A__ and __I__ are monomer and initiator concentrations, respectivel
The enantiospecific synthesis of both antipodes of a-methylaspartic acid from (S)tryptophan is described with the key steps being alkylation of the hexabydropytroloindole 4, oxidative degradation of indoles and, for the preparation of the (R)-isomer, Barton reductive decarboxylation. The asymmetric