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Enzymic oxidation of methotrexate and aminopterin

✍ Scribed by David G. Johns; Anthony T. Iannotti; Alan C. Sartorelli; Barbara A. Booth; Joseph R. Bertino

Book ID
118933095
Publisher
Elsevier Science
Year
1964
Tongue
English
Weight
222 KB
Volume
3
Category
Article
ISSN
0024-3205

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Maternal exposures to aminopterin and methotrexate have been associated with a pattern of malformation which includes prenatal-onset growth deficiency, severe lack of ossification of the calvarium, hypoplastic supraorbital ridges, small, lowset ears, micrognathia, and limb abnormalities. We report o