Enzymic optical resolution and flash vacuum thermolysis in concert for the synthesis of optically active cyclopentenones
β Scribed by A.J.H. Klunder; W.B. Huizinga; P.J.M. Sessink; B. Zwanenburg
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- French
- Weight
- 259 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0040-4039
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Enantiomerically pure 1-chlorovinyl p-tolyl sulfoxides having two different substituents at the 2-position were synthesized from unsymmetrical ketones and (R)-(-)-chloromethyl p-tolyl sulfoxide in three steps. Treatment of the 1-chlorovinyl p-tolyl sulfoxides with cyanomethyllithium at -78Β°C to room
Part of the Ph.D. thesis of F.G.