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Enzyme-Mediated Protein Haptenation of Dapsone and Sulfamethoxazole in Human Keratinocytes: I. Expression and Role of Cytochromes P450

✍ Scribed by Vyas, P. M.

Book ID
125544253
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2006
Tongue
English
Weight
467 KB
Volume
319
Category
Article
ISSN
0022-3565

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The aim of this study was to test suitable culture conditions for maintaining normal cellular cytoarchitecture and inducibility of P450 enzymes in primary cultures of human hepatocytes by prototypical inducers. The selectivity and sensitivity of a sandwich culture system were determined by treating