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Enzyme induction of renal transport mechanism by rifampicin in man?

✍ Scribed by N.H. Brockmeyer; H. Heidemann; E.E. Ohnhaus


Book ID
118385434
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
160 KB
Volume
33
Category
Article
ISSN
0163-7258

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✍ Matthew D. Merrell; Lisa M. Augustine; Angela L. Slitt; Nathan J. Cherrington πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 325 KB

## Abstract Coordinate regulation of Phase‐I and ‐II enzymes with xenobiotic transporters has been shown after treatment with microsomal enzyme inducers. The chemopreventive agent oltipraz (OPZ) induces Phase‐I and ‐II drug‐metabolizing enzymes such as CYP2B and NQO1. The purpose of this study was