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Enzyme immunoassay for the detection of antibody to hepatitis E virus based on synthetic peptides

✍ Scribed by M.O. Favorov; Y.E. Khudyakov; H.A. Fields; N.S. Khudyakova; N. Padhye; M.J. Alter; E. Mast; L. Polish; T.L. Yashina; D.M. Yarasheva; G.G. Onischenko; H.S. Margolis


Book ID
119115468
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
851 KB
Volume
46
Category
Article
ISSN
0166-0934

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To develop an enzyme immunoassay (EIA) for IgM antibody t o hepatitis E virus (HEW (IgM anti-HEV) and IgG antibody t o HEV (IgG anti-HEV), a synthetic gene encoding several liner immunodominant antigenic epitopes f r o m HEV structural proteins was assembled as a chimeric recombinant mosaic protein