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Enzymatic Two-Step Synthesis of N-Acetyl-neuraminic Acid in the Enzyme Membrane Reactor

✍ Scribed by Dipl.-Chem. Udo Kragl; Dr. Daniel Gygax; Dr. Oreste Ghisalba; Prof. Dr. Christian Wandrey


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
263 KB
Volume
30
Category
Article
ISSN
0044-8249

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✦ Synopsis


V = 1078.3(5) x lo6 pm3, psalsd = 1.089 g ~m -~, Z = 2, crystal size 0.3 x 0.3 x 0.9 mm3, 173 K, Cu,,, radiation, Enraf-Nonius CAD4, scan width 2.25 <8 < 76.5",4202 symmetry-independent and significant reflections [IF1 >3u(F)] structure solution by direct methods (SHELXS-86 [6]) supplemented by difference Fourier and LSQ calculations (SHELX-76) [6], 288 refined parameters, R = 0.0610, R , = 0.0608 ( w = l/u2(fl), all non-hydrogen atoms were refined with anisotropic temperature factors; the positions of H122 and H123 were determined directly, those of the remaining H atoms were place at calculated positions in the refinement K6.71. [14] S .