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Enzymatic synthesis of ribonucleoside-5′-phosphates from some N6-substituted adenosines

✍ Scribed by Marcel Doree; Claude Terrine


Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
643 KB
Volume
12
Category
Article
ISSN
0031-9422

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Chemical modification of 5a-carba-b-dl-fucopyranosylamine (3) generated six N-substituted derivatives 9a-f, among which N-octyl 9b, decyl 9c, and phenylbutyl ones 9f were found to be very strong b-galactosidase as well as b-glucosidase inhibitors. The inhibitory activity appeared attributable to d-e