Enzymatic synthesis of peptides containing unnatural amino acids
โ Scribed by M.M. Fernandez; A.O. Margot; C.A. Falender; H.W. Blanch; D.S. Clark
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 1020 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0141-0229
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
It is now routine using automatic Edman microsequencing to determine the primary structure of peptides or proteins containing natural amino acids; however, a deficiency in the ability to readily sequence peptides containing unnatural amino acids remains. With the advent of synthetic peptide chemistr
## Abstract For Abstract see ChemInform Abstract in Full Text.
An unnatural peptide-based library, bound on a solid support, was screened for double-stranded-DNA (dsDNA)-binding ligands. For this purpose, fluorescein and rhodamine were used to label the single-stranded oligodeoxynucleotides. Beads containing products with affinity to dsDNA turned red in visible