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Enzymatic synthesis of delta sleep-inducing peptide

✍ Scribed by SAKINA, KIYOSHI ;KAWAZURA, KEIKO ;MORIHARA, KAZUYUKI


Book ID
115098748
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
597 KB
Volume
31
Category
Article
ISSN
0367-8377

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## Abstract The __Ξ±__,__Ξ²__‐dehydro precursor of the delta sleep‐inducing peptide (DSIP) for tritiation was prepared prior to tritiation using a 3+6 fragment coupling strategy on a solid support. The first fragment, __Ξ±__,__Ξ²__‐dehydrotripeptide, was prepared in solution in five steps in 79% overal