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Enzymatic synthesis of Cephalexin in recyclable aqueous two-phase systems composed by two pH responsive polymers

✍ Scribed by Li, Shutao; Cao, Xuejun


Book ID
124114692
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
522 KB
Volume
90
Category
Article
ISSN
1369-703X

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Enzymatic synthesis of cephalexin in aqu
✍ Dong-Zhi Wei; Jian-Hang Zhu; Xue-Jun Cao πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 English βš– 77 KB

Cephalexin was synthesized in aqueous two-phase systems (ATPSs) by using penicillin G acylase (PGA) (penicillin amidohydrolase, EC3.5.1.11) as a catalyst and 7-aminodeacetoxicephalosporanic acid (7-ADCA) and phenylglycine methyl ester (PGME) as substrates. In the ATPS composed of 20% (w/w) PEG 400 a