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Enzymatic synthesis of activated esters and their subsequent use in enzyme-based peptide synthesis

✍ Scribed by Timo Nuijens; Claudia Cusan; Annette C.H.M. Schepers; John A.W. Kruijtzer; Dirk T.S. Rijkers; Rob M.J. Liskamp; Peter J.L.M. Quaedflieg


Book ID
113804836
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
411 KB
Volume
71
Category
Article
ISSN
1381-1177

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Enzymatic Peptide Synthesis in Frozen Aq
✍ Sabine Gerisch; Hans-Dieter Jakubke πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 84 KB πŸ‘ 1 views

The ability of the endopeptidase a-chymotrypsin (EC 3.4.21.1) to catalyse the reaction of various N aunprotected di-and tripeptide ester derivatives with H-Leu-NH 2 , and with a series of C-terminal free di-and tripeptides at ΓΏ15 C in frozen aqueous solution was investigated. The enzyme is able to s