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Enzymatic S-methylation of 6-n-propyl-2-thiouracil and other antithyroid drugs

✍ Scribed by Raymond H. Lindsay; Billie sue Hulsey; Hassan Y. Aboul-Enein

Book ID
115772505
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
663 KB
Volume
24
Category
Article
ISSN
0006-2952

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πŸ“œ SIMILAR VOLUMES

Synthesis of 6-n-propyl-2-thiouracil-6βˆ’1
Synthesis of 6-n-propyl-2-thiouracil-6βˆ’14C
✍ D. P. Thornhill; D. S. Sitar πŸ“‚ Article πŸ“… 1971 πŸ› John Wiley and Sons 🌐 French βš– 202 KB

## Abstract 6‐n‐Propyl‐2‐thiouracil‐6βˆ’^14^C was prepared from sodium butyrate‐1βˆ’^14^C, with a radiochemical yield of 34%. Butyryl chloride‐1βˆ’^14^C was prepared from butyric acid‐1βˆ’^14^C and condensed with sodio ethylacetoacetate to yield ethyl β‐oxohexanoateβ€Ξ²βˆ’^14^C. The β‐keto ester was condensed

Synthesis of S-methyl-6-propyl-2-thioura
Synthesis of S-methyl-6-propyl-2-thiouracil-35S and 6-propyluracil-2-14C
✍ Hassan Y. Aboul-Enein πŸ“‚ Article πŸ“… 1974 πŸ› John Wiley and Sons 🌐 French βš– 71 KB

Two o f t h e m i n o r m e t a b o l i t e s o f t h e a n t i t h y r o i d d r u g 6 -p r o p y l -2t h i o u r a c i l ( I ) have been i s o l a t e d f r o m r a t u r i n e i d e n t i f i e d as S-methyl-6 -p r o p y l -2 -t h i o u r a c i l