The reduction of SIRT1 in livers of old
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Jingling Jin; Polina Iakova; Yanjun Jiang; Estela E. Medrano; Nikolai A. Timchen
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Article
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2011
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John Wiley and Sons
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English
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Age declines liver functions, leading to the development of age-associated diseases. A member of the sirtuins family, SIRT1, is involved in the control of glucose homeostasis and fat metabolism. Because aging livers have alterations in glucose and fat metabolism, we examined a possible role of SIRT1