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Enzymatic Racemization of Amines Catalyzed by Enantiocomplementary ω-Transaminases

✍ Scribed by Dr. Dominik Koszelewski; Barbara Grischek; Dr. Silvia M. Glueck; Prof. Wolfgang Kroutil; Prof. Kurt Faber


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
264 KB
Volume
17
Category
Article
ISSN
0947-6539

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Deracemisation of α-Chiral Primary Amine
✍ Dominik Koszelewski; Dorina Clay; David Rozzell; Wolfgang Kroutil 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 141 KB

## Abstract Racemic α‐chiral primary amines were deracemised to optically pure amines in up to >99 % conversion and >99 % __ee__ within 48 h. The deracemisation was a result of a stereoinversion of one amine enantiomer; the formal stereoinversion was achieved by a one‐pot, two‐step procedure: in th