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Enzymatic production of 2-amino-2,3-dimethylbutyramide by cyanide-resistant nitrile hydratase

✍ Scribed by Zhi-Jian Lin; Ren-Chao Zheng; Ya-Jun Wang; Yu-Guo Zheng; Yin-Chu Shen

Book ID
106310096
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
481 KB
Volume
39
Category
Article
ISSN
1476-5535

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Production ofS-(+)-2-phenylpropionic aci
Production ofS-(+)-2-phenylpropionic acid from (R,S)-2-phenylpropionitrile by the combination of nitrile hydratase and stereoselective amidase inRhodococcus equiTG328
✍ Thomas Gilligan; Hideaki Yamada; Toru Nagasawa πŸ“‚ Article πŸ“… 1993 πŸ› Springer 🌐 English βš– 687 KB

A new soil isolate, tentatively identified as Rhodococcus equi TG328, was found to be effective in the production of S-( + )-2-phenylpropionic acid from (R,S)-2-phenylpropionitrile. The conversion is catalysed by two enzymes. First, a nitrile hydratase converts the (R,S)-nitrile to (R,S)-2-phenylpro