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Enzymatic monooxygenation of halogen atoms: cytochrome P-450 catalyzed oxidation of iodobenzene by iodosobenzene

✍ Scribed by Burka, Leo T.; Thorsen, Alice; Guengerich, F. Peter

Book ID
126416927
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
297 KB
Volume
102
Category
Article
ISSN
0002-7863

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## Abstract Modeling, mutagenesis, and kinetic studies have demonstrated that the substrate‐binding site of cytochrome P450 is composed of multiple interactive regions that are capable of simultaneously binding two or more xenobiotics. Substrate molecules can interact with each other after docking.