An Enzymatic Assay for Quantifying Sphin
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Xingxuan He; Fei Chen; Shimon Gatt; Edward H. Schuchman
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Article
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2001
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Elsevier Science
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English
β 171 KB
## Sphingomyelin is an important lipid component of cell membranes and lipoproteins which can be hydrolyzed by sphingomyelinases into ceramide and phosphorylcholine. The type A and B forms of Niemann-Pick disease (NPD) are lipid storage disorders due to the deficient activity of the enzyme acid sp