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Enzymatic hydrolysis of sphingomyelin liposomes by normal tissues and tissues from patients with niemann-pick disease

✍ Scribed by A. Poulos; P. Shankaran; C.S. Jones; J.W. Callahan


Book ID
115738873
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
340 KB
Volume
751
Category
Article
ISSN
0005-2760

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## Sphingomyelin is an important lipid component of cell membranes and lipoproteins which can be hydrolyzed by sphingomyelinases into ceramide and phosphorylcholine. The type A and B forms of Niemann-Pick disease (NPD) are lipid storage disorders due to the deficient activity of the enzyme acid sp