Enzymatic formation of modular cell-instructive fibrin analogs for tissue engineering
β Scribed by Martin Ehrbar; Simone C. Rizzi; Ruslan Hlushchuk; Valentin Djonov; Andreas H. Zisch; Jeffrey A. Hubbell; Franz E. Weber; Matthias P. Lutolf
- Book ID
- 108069805
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 793 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0142-9612
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π SIMILAR VOLUMES
## Abstract A composite scaffold of poly(Lβlacticβ__co__βglycolic acid) (PLGA) microspheres and fibrin gel was fabricated by blending fibrinogenβimmobilized PLGA microspheres with fibrinogen and thrombin solution. The PLGA microspheres with a size of 70 βΌ 100 ΞΌm were aminolyzed in a hexanediamine/_
This study assessed the role of immobilized cell adhesion moieties on controlling the cellular attachment, adhesion and phenotype of cardiac muscle cells towards developing scaffolds for cardiac muscle tissue engineering. Collagen I, laminin and the cell-adhesive oligopeptide, arginine-glycine-aspar